Search on: TAU PROTEIN 
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Descriptor English:   tau Proteins 
Descriptor Spanish:   Proteínas tau 
Descriptor Portuguese:   Proteínas tau 
Synonyms English:   tau Protein
Protein, tau
Proteins, tau  
Tree Number:   D12.776.220.600.450.510
D12.776.631.560.510
Definition English:   Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES). 
See Related English:   Tauopathies
 
History Note English:   1992; use TAU (NM) 1977-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   30290 
Unique Identifier:   D016875 

Occurrence in VHL:
 

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